gabaar β2 Search Results


92
Bioss anti gabaar β2 3 antibody
Anti Gabaar β2 3 Antibody, supplied by Bioss, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Danaher Inc gabaar β2
Information of the primary antibodies used in this study
Gabaar β2, supplied by Danaher Inc, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Merck KGaA anti-gabaa receptor β2/3 chain antibody mab341
Information of the primary antibodies used in this study
Anti Gabaa Receptor β2/3 Chain Antibody Mab341, supplied by Merck KGaA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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94
Alomone Labs α btx
Zebrafish α9 and α9α10 nAChRs are reversibly blocked by <t>ɑ-Btx.</t> Responses to 10 μM (α9) or 300 μM (α9α10) ACh either alone, in the presence of 100 <t>nM</t> <t>α-Btx</t> or after washing with control bath solution for 5 min, in oocytes expressing zebrafish α9 or α9α10 nAChRs are shown. Oocytes were pre-incubated with 100 nM α-Btx for 1 min prior to the addition of the agonist. α-Btx inhibited ACh responses by 93.70 ± 2.17% (n = 2) and 85.16 ± 6.86% (n= 2), respectively.
α Btx, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 94 stars, based on 1 article reviews
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96
PhosphoSolutions rabbit anti β2 subunit
Zebrafish α9 and α9α10 nAChRs are reversibly blocked by <t>ɑ-Btx.</t> Responses to 10 μM (α9) or 300 μM (α9α10) ACh either alone, in the presence of 100 <t>nM</t> <t>α-Btx</t> or after washing with control bath solution for 5 min, in oocytes expressing zebrafish α9 or α9α10 nAChRs are shown. Oocytes were pre-incubated with 100 nM α-Btx for 1 min prior to the addition of the agonist. α-Btx inhibited ACh responses by 93.70 ± 2.17% (n = 2) and 85.16 ± 6.86% (n= 2), respectively.
Rabbit Anti β2 Subunit, supplied by PhosphoSolutions, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/gabaar+%CE%B22/Anti-GABAA+Receptor+%C3%9F2+Antibody/bio_rxiv__2023__12__04__569994-201-80-84
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CoCensys Inc human gabaa receptor subunit (α1,α2,α3,β1,β2,β3, γ2, δ) cdna clones
Zebrafish α9 and α9α10 nAChRs are reversibly blocked by <t>ɑ-Btx.</t> Responses to 10 μM (α9) or 300 μM (α9α10) ACh either alone, in the presence of 100 <t>nM</t> <t>α-Btx</t> or after washing with control bath solution for 5 min, in oocytes expressing zebrafish α9 or α9α10 nAChRs are shown. Oocytes were pre-incubated with 100 nM α-Btx for 1 min prior to the addition of the agonist. α-Btx inhibited ACh responses by 93.70 ± 2.17% (n = 2) and 85.16 ± 6.86% (n= 2), respectively.
Human Gabaa Receptor Subunit (α1,α2,α3,β1,β2,β3, γ2, δ) Cdna Clones, supplied by CoCensys Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human gabaa receptor subunit (α1,α2,α3,β1,β2,β3, γ2, δ) cdna clones - by Bioz Stars, 2026-09
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N/A
Gene Silencers generally consist of pools of three to five target-specific 19-25 nucleotide sequences in length. For independent verification of GABAA Rβ2 gene silencing results, individual duplex components or plasmids are also available upon request.
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N/A
CRISPR/Cas9 KO Plasmids consists of GABAA Rβ2-specific 20 nt guide RNA sequences derived from the GeCKO (v2) library. For CRISPR gene knockout, gRNA sequences direct the Cas9 protein to induce a site-specific double strand break
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N/A
CRISPR/Cas9 KO Plasmids consists of GABAA Rβ2-specific 20 nt guide RNA sequences derived from the GeCKO (v2) library. For CRISPR gene knockout, gRNA sequences direct the Cas9 protein to induce a site-specific double strand break
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N/A
CRISPR/Cas9 KO Plasmids consists of GABAA Rβ2-specific 20 nt guide RNA sequences derived from the GeCKO (v2) library. For CRISPR gene knockout, gRNA sequences direct the Cas9 protein to induce a site-specific double strand break
  Buy from Supplier

N/A
Gene Silencers generally consist of pools of three to five target-specific 19-25 nucleotide sequences in length. For independent verification of GABAA Rβ2 gene silencing results, individual duplex components or plasmids are also available upon request.
  Buy from Supplier

Image Search Results


Information of the primary antibodies used in this study

Journal: Molecular Neurodegeneration

Article Title: Enhancing GABAergic signaling ameliorates aberrant gamma oscillations of olfactory bulb in AD mouse models

doi: 10.1186/s13024-021-00434-7

Figure Lengend Snippet: Information of the primary antibodies used in this study

Article Snippet: GABAAR-β2 , Abcam , ab156000 , Rabbit , , 1:10000.

Techniques:

Zebrafish α9 and α9α10 nAChRs are reversibly blocked by ɑ-Btx. Responses to 10 μM (α9) or 300 μM (α9α10) ACh either alone, in the presence of 100 nM α-Btx or after washing with control bath solution for 5 min, in oocytes expressing zebrafish α9 or α9α10 nAChRs are shown. Oocytes were pre-incubated with 100 nM α-Btx for 1 min prior to the addition of the agonist. α-Btx inhibited ACh responses by 93.70 ± 2.17% (n = 2) and 85.16 ± 6.86% (n= 2), respectively.

Journal: bioRxiv

Article Title: Unravelling the molecular players at the cholinergic efferent synapse of the zebrafish lateral line

doi: 10.1101/2020.07.09.196246

Figure Lengend Snippet: Zebrafish α9 and α9α10 nAChRs are reversibly blocked by ɑ-Btx. Responses to 10 μM (α9) or 300 μM (α9α10) ACh either alone, in the presence of 100 nM α-Btx or after washing with control bath solution for 5 min, in oocytes expressing zebrafish α9 or α9α10 nAChRs are shown. Oocytes were pre-incubated with 100 nM α-Btx for 1 min prior to the addition of the agonist. α-Btx inhibited ACh responses by 93.70 ± 2.17% (n = 2) and 85.16 ± 6.86% (n= 2), respectively.

Article Snippet: All drugs were obtained from Sigma-Aldrich, except α-Btx and apamin that were purchased from Alomone.

Techniques: Expressing, Incubation

ACh-mediated inhibition of evoked Ca 2+ signals is blocked by α-Btx and apamin. A , Top , Representative temporal curves of mechanosensitive Ca 2+ responses of 4 HC, before (red) and after the application of 10 μM α-Btx (green). Bottom , Mechanosensitive Ca 2+ signals show no significant difference before and after 10 μM α-Btx treatment (Extra: Mdn ΔF/F0= 0.509 IQR: 0.252-1.134 Vs. α-Btx: Mdn ΔF/F0= 0.534 IQR: 0.331-1.325, n = 25, W= −45, p= 0.5449, MPRBC = 0.138). B , Top , Representative temporal curves of mechanosensitive Ca 2+ responses of 4 HC, after the application of 10 μM α-Btx (green) and after the co-application of 1 mM ACh and 10 μM α-Btx (blue). Bottom , When co-applied with 10 μM α-Btx, ACh-mediated inhibition is blocked (n = 25, W= −87, p= 0.2521, MPRBC = 0.268). C , Top , Representative temporal curves of mechanosensitive Ca 2+ responses of 4 hair cells, before (red) and after the application of 10 μM apamin (orange). Bottom , Mechanosensitive Ca 2+ signals show no significant difference before and after 10 μM apamin treatment (Extra: Mdn ΔF/F0= 0.599 IQR: 0.243-1.216 Vs. Apa: Mdn ΔF/F0= 0.567 IQR: 0.191-1.040, n = 41, W= −91, p= 0.5554, MPRBC = 0.106). D , Top , Representative temporal curves of mechanosensitive Ca 2+ responses of 4 HC, after the application of 10 μM apamin (orange) and after the co-application of 1 mM ACh and 10 μM apamin (blue). Bottom , ACh-mediated inhibition is blocked by 10 μM apamin (n = 60, W= −322, p= 0.2359, MPRBC = 0.1759). A Wilcoxon matched-pairs signed rank test was used in all cases. Extra: Extracellular imaging solution, ACh: Acetylcholine, α-Btx: α-bungarotoxin, Apa: Apamin. Horizontal scale bar in A , B , C and D : 1.5 sec, vertical scale bar in A , B , C and D : 25% ΔF/F0. Duration of the stimulus is indicated by gray lines below each trace.

Journal: bioRxiv

Article Title: Unravelling the molecular players at the cholinergic efferent synapse of the zebrafish lateral line

doi: 10.1101/2020.07.09.196246

Figure Lengend Snippet: ACh-mediated inhibition of evoked Ca 2+ signals is blocked by α-Btx and apamin. A , Top , Representative temporal curves of mechanosensitive Ca 2+ responses of 4 HC, before (red) and after the application of 10 μM α-Btx (green). Bottom , Mechanosensitive Ca 2+ signals show no significant difference before and after 10 μM α-Btx treatment (Extra: Mdn ΔF/F0= 0.509 IQR: 0.252-1.134 Vs. α-Btx: Mdn ΔF/F0= 0.534 IQR: 0.331-1.325, n = 25, W= −45, p= 0.5449, MPRBC = 0.138). B , Top , Representative temporal curves of mechanosensitive Ca 2+ responses of 4 HC, after the application of 10 μM α-Btx (green) and after the co-application of 1 mM ACh and 10 μM α-Btx (blue). Bottom , When co-applied with 10 μM α-Btx, ACh-mediated inhibition is blocked (n = 25, W= −87, p= 0.2521, MPRBC = 0.268). C , Top , Representative temporal curves of mechanosensitive Ca 2+ responses of 4 hair cells, before (red) and after the application of 10 μM apamin (orange). Bottom , Mechanosensitive Ca 2+ signals show no significant difference before and after 10 μM apamin treatment (Extra: Mdn ΔF/F0= 0.599 IQR: 0.243-1.216 Vs. Apa: Mdn ΔF/F0= 0.567 IQR: 0.191-1.040, n = 41, W= −91, p= 0.5554, MPRBC = 0.106). D , Top , Representative temporal curves of mechanosensitive Ca 2+ responses of 4 HC, after the application of 10 μM apamin (orange) and after the co-application of 1 mM ACh and 10 μM apamin (blue). Bottom , ACh-mediated inhibition is blocked by 10 μM apamin (n = 60, W= −322, p= 0.2359, MPRBC = 0.1759). A Wilcoxon matched-pairs signed rank test was used in all cases. Extra: Extracellular imaging solution, ACh: Acetylcholine, α-Btx: α-bungarotoxin, Apa: Apamin. Horizontal scale bar in A , B , C and D : 1.5 sec, vertical scale bar in A , B , C and D : 25% ΔF/F0. Duration of the stimulus is indicated by gray lines below each trace.

Article Snippet: All drugs were obtained from Sigma-Aldrich, except α-Btx and apamin that were purchased from Alomone.

Techniques: Inhibition, Imaging